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[music] kathy: welcome to biobalance health cast.i’m dr. kathy maupin. brett: and i’m brett newcomb. and normallyon these podcast we talk about various elements of hormones and hormone replacement and conversationaltopics because we’re trying to understand the topic of hormones and how they work inthe body. today we’re not going to talk



armour thyroid weight loss

armour thyroid weight loss, about testosterone we’re going to talk aboutanother element in the puzzle. we’re going to talk about the thyroid. because what hasemerged is a lot of information that says the thyroid, whether it’s under functioning,over functioning or appropriately functioning, is just as critital in a healthy stable lifeafter menopause. and so we want to talk about


the thyroid because a lot of time issues withthe thyroid are not diagnosed or not identified. sometimes the lab results don’t give a clearpicture or an accurate picture. i mean there are a lot of issues that can occur. and thereason we want to talk about this today is april 23 just two days ago an article cameout in the archives of internal medicine looking at sub-clinical hypothyroidism and fatal ornonfatal cardiovascular events. so first let’s define some terms. talk us through hypothyroidism,hyperthyroidism and subclinical. what do those terms mean?kathy: hypothyroidism is a very low thyroid. your thyroid is in your neck, it runs yourmetabolism. it runs how warm you are how you metabolize your calories.brett: so i’m not really fat, i just have


a low metabolism.kathy: yea, see? or your thyroid’s low, causing that. and thyroid patient who havea low thyroid have swelling all over. they look very swollen in general. or they alsohave a very slow intestine. so they usually have constipation, unless they have some othergi disease. they also gain weight rapidly and don’t lose it. they feel cold when othersare hot. their basal temperatures are low. usually they stop having periods or have irregularcycles if they’re premenopausal. they have infertility. the thyroid manages everythingin your body. it’s not as universal as the pituitary that runs every single gland inyour body. but the most universal gland the thyroid. thyroid takes care of every singlecell in your body, and has receptor sites


on every cell. so having a thyroid that worksoptimally is very important for your lipids. your cholesterol goes up if you have low thyroid.so if you have high cholesterol in the old days we used to check for low cholesterolwith a low thyroid when we got results back that showed a low thyroid. and if the cholesterolwas elevated we treated thyroid and the cholesterol came down. so it affects everything.brett: and now they just treat they cholesterol and they don’t assess the thyroid.kathy: right, and it’s bothersome because it’s not really treating the problem, it’streating a symptom of the problem. brett: yea it’s like putting a gas additivein your car to get better mileage instead of tuning your car up.kathy: that’s right and thyroid affects


so many other things. they could kill 20 birdswith one stone. they could help people lose weight. you know doctors could actually tendto what’s really bothering the patient. which is i can’t lose weight even when iexercise every day and eat very little. that’s really what thyroid patients say.brett: so medicine by symptom management is more expensive.kathy: well if you’re looking at one symptom. brett: well you treat that one and they comeback for the next one. kathy: that’s right, it is. and it’s manymore drugs, because cholesterol drugs are very expensive. and thyroid is very cheap.so for us to actually treat symptoms and prevent illness it’s much more economical to treatwith a thyroid medication if that’s the


problem. now hyperthyroidism is different.hyperthyroidism is the reverse. patients are very nervous and anxious their hearth rategoes up. they lose weight quickly they’re hot all the time. they move around all thetime. it’s kind of like an a.d.d. kind of thing in general.brett: they’re wired. kathy: they’re wired, but it’s not a psychologicalproblem it’s a thyroid problem. and often time it’s misdiagnosed. because if you don’ttake a temperature you can’t find a fever, if you don’t test the thyroid you can’tfind hyperthyroidism. but when it is found usually drugs are giving to shut it down,or radiation’s given. brett: you just used some terminology you’retalking about testing it. earlier in the conversation


you’re going through a list of symptomsthat come out of a clinical interview. if you sit down with a patient and you say tellme what’s going on you with you. are you constipated, do you get cold easily? and yougo through this checklist in your head that tells you as an experienced physician, i needto be looking at a thyroid problem. then you get a lab test? but sometime the lab testdoesn’t say thyroid problem but all the symptoms do. then what do you do with that?kathy: well that’s called subclinical hyperthyroidism. brett: that’s what we’re talking aboutoddly enough. kathy: and inversely it is if you have a thyroidtest that shows hyperthyroidism but no symptoms. this study says that should be treated aswell. but lab tests that show hypothyroidism


without symptoms and symptoms without thelab test are considered subclinical and they should be treated and they should be treatedfor many reasons but studies have to be honed down usually to one variable. and this variablewas the rate of heart disease and can replacing thyroid, the question they wanted to answerwas, can we prevent heart disease and heart attacks and fatal heart problems by replacingthyroid? now that’s very conservative in terms of money and that’s, for the patient,that’s awesome, that’s preventative medicine. so that’s what this study was asking. that’sthe question they were asking. brett: for hypo not for all thyroids. forhypothyroid. kathy: yes and there’s lots of other diseasesthat you can have associated with the thyroid.


but we’re talking about a slow or a lowor inactive thyroid. and that is what’s most dangerous in terms of heart disease.brett: ok, so they’re trying to isolate the variables out in terms of looking at theheart disease issues, either fatal or non fatal heart disease and we’ll differentiateamong those in a minute, and why there’s a concern. but if we’re looking at heartdisease issue and we identify one variable, the thyroid and if the thyroid is under performing,is there more likelihood of a heart issue over time? and if you treat the underperformingthyroid, do you alleviate the risk of the heart issues?kathy: right because when you do a study, just because you find out that a low thyroidcauses this, doesn’t mean that treating


that low thyroid will prevent it.brett: so it could be a corollary as opposed to causation. it could be just simultaneousevents. so they look for the linkage. kathy: they look for the linkage and that’sa very good study to look for the linkage and they found that not only does hyperthyroidismcause non fatal and fatal heart events but they also found out by giving and replacingthyroid to an optimal level will also prevent this and that’s very important because itadded the variable of thyroid and heart disease and tied them together because now we canprevent it. brett: right and fairly inexpensively andfairly easily because thyroid medicines are not that expensive and they’re pretty easyto take with side effects not being an issue


and then it increases the odds that you won’thave an ischemic heart disease. kathy: ischemic means that you won’t haveapoxy or no oxygen going to the heart itself. usually that means a blockage of a blood vesselwith arthrosclerosis or cholesterol deposits. but it can be any kind of low oxygen levelthat causes damage to the heart muscle. brett: so obviously or i think obviously fatalheart disease is self-explanatory and we know why that’s an issue. but what about nonfatal heart issues? what’s the concern there? kathy: most people don’t realize that whenyou have a heart attack that a heart attack means that part of your heart muscle has beendamaged. the vessel going to it was blocked so that you could not get enough oxygen toan area of the heart. there are many vessels


that go to feed the heart. even if one ofthem is blocked it can cause that muscle to die. and the heart muscle depends on an entirecircumference of muscle squeezing. so if part of that doesn’t squeeze as well then youend up not getting the blood flow to your legs, not getting blood flow to your brain.it decreases your cardiac output. it makes the work of the heart harder. what’s presentand accounted for has to work harder to get blood to the rest of the body. and your kidneyswon’t work as well, you won’t feel as good, and you’ll be tired. so often timesif you have a non fatal heart attack from lack of oxygen to the muscle, you’re debilitated.and that’s a terrible outcome to have, especially after menopause. especially even in men whoare older their testosterone is down, women’s


testosterone is down. by the time we usuallyhave the hearts problems, we are post-menopausal, post-andropausal.brett: yea, typically. kathy: and then the muscle doesn’t growback and so then we’re left with a life that is confined to a chair, you can’t exercise,you may have to use oxygen. and that’s a terrible way to live. it takes productivityaway from us. it takes the joy of life and the joy of just being able to produce something,go to work, take care of our kids. so that’s a huge deal and if we can prevent that throughgiving levothyroixine which is the generic of synthroid or armour thyroid or cytomelthere are many different forms of thyroid they just use levothyroixine in there testsbecause it was a generic and most inexpensive.


but if we can use that and replace what’smissing in terms of our other hormones like testosterone and estrogen then we have eamuch lower risk of dying of heart disease or even damaging our heart because it’salso known that testosterone helps us repair the heart even after hypoxia which is lowoxygen. so we are able then to take what we know and add it to this to create the mostpreventive situation for a patient. give them back their thyroid, give them back their testosterone,give them back their estrodial if they’re women and that puts them in the best placeto resist having a fatal or non fatal debilitating heart attack.brett: so the quality of life is a factor here because you tend to think heat attackpeople die. but most people don’t die from


a heart attack.kathy: i’d rather die than have a debilitating heart attack. because that to me my life wouldbe over as i know it. and that would be very, very difficult but the fact that i take testosteroneand i take estrodial, that would help me recover from that. in fact i have one patient whois male and is 64. and he had a terrible heart attack and he had just started taking testosterone.and it damaged so much of his heart that they said he would only get a certain amount ofhis cardiac output back. and he may not be able to exercise and he may not be able tolive his life. brett: and his cardiac doc looking at whatyou proposed for him looked at if from a standpoint of what dr. maupin wants to do going to causeany damaging side effects? and he couldn’t


find any so he said i don’t believe it’sgoing t hurt him but it’s not going to help. so you put him on this treatment protocol.how did he change? kathy: this was continuing to replace histestosterone. we had already started that but he hadn’t been onl it long enough toprotect his heart. so when he had this heart attack. he said i really want testosteroneit makes me feel better, it makes me leaner it’s going to help me recover he didn’treally think about the heart muscle. he thought about all the other muscles. but what it didwas help repair his heart muscle. brett: that’s awesome.kathy: i know. it’s amazing. and his doctor, i sent all of the research; i sent tons ofpaper so his cardiologist could make a decision


on his own. and i waited on that decision.i know him also socially and i see him out and he is just as energetic and awesome asever was brett: your patient, not his doctor.kathy: no, no, no, sorry, my patient. and his doctor is amazed. he’s never seen anyonewith the damage he had come back to normal. and he’s normal.brett: yea and the reason we’re talking about this part and we’ve shifted back intotestosterone and testosterone replacement is the study that was reported in the archivesof internal medicine did find a positive uptick in treating hypothyroidism in younger patients.but for those 70 and older the incident of heart disease issues didn’t improve. itdidn’t get worse but it didn’t get better.


so what they said was that if we catch youyoung enough and we treat your thyroid, we can avoid or delay these events. if you’reolder then we can’t say the same thing. we don’t know what to do with that but wecan’t say the same thing. and your argument is that if they replace in the elderly populationin the elderly population that replaces testosterone their overall quality of life and muscle strengthwill get better. kathy: and muscles of the heart.brett: and particularly the muscle of the heart, because this man is a good exampleof that. kathy: yea he’s an excellent example andi’m hoping to see more patients from this cardiologist who now has seen it work sendingme patients who i can then help get back to


the usual life. because we identify with patientswho we’re very much like. and the patients that come to see me want to be productiveand they want to go back to work and they want to exercise and they want to have a healthylife so they’re looking for that. and i don’t want to have a heart attack, or somethinglike that, impair them from their life. they need it all. they need their thyroid if they’velost it or if it’s decreased. they need their testosterone and they need their estrodialbecause estrodial is also cardio protective. brett: you know it must be phenomenally pleasingand comforting to you to make that kind of impact like that in somebody’s life. i meanthis guy comes in. he’s nearly dying, he’s not able to walk he’s not able to exercise.kathy: he literally looked gray.


brett: his skin color is off because his oxygencontent is off. and in a few months of treatment he’s walking, he’s exercising, his coloris good, his heart muscle is stronger. kathy: he was dancing to the beatles the lasttime i saw him. and he was amazing. so he looks like he did, actually he looks betterthan he did because he lost weight. this scared him, he lost weight and so he looks even betterthan he did three years ago. so this study for me is documenting what i always believed.that if someone has symptoms of thyroid without the lab or the lab without the symptoms theyshould be treated. and there’s many more reason, losing weight and decreasing you’reswelling and decreasing your cholesterol. brett: regulating body temperature, comfort,all those things. and you know it’s not


a new topic. cardiologists are looking atit now, but gynecologists were looking at it as long ago as 2006. you were talking abouta study in the gynecological journals about hypothyroidism but you had an interestingtwist to your understanding of why they were looking at it.kathy: well in obgyn the center of attention is on fertility and on young women. and thequestions was should we even look for low thyroid in young women and it was for fertility.because if you have. brett: so if you’re not fertile and you’renot trying to be fertile than they are not as focused on or concerned about you.
kathy: i mean, i’m a obgyn and i’m board certified and i’m a fellow in theamerican college of obgyn and i had very little


training in post menopausal care. it was justgive them hormones or don’t give them hormones, that was it. and hormones meant estrogen andprogesterone or just estrogen. brett: so it didn’t mean thyroid. and itdidn’t mean testosterone. kathy: it didn’t mean testosterone. andthere was very little about caring for people after the age of 40 something when they stoppedproducing. because we do deliver babies and we treat infertility so that’s primarilyone of the things we are trained to do and we have lots of hours in those areas. butwe have very few hours in clinical management in the menopausal patient. and when i readthis study and i pulled it i pulled it because it’s hypothyroidism and i treat hypothyroidismof all ages and i always have because i’ve


had this problem myself since i was in my20’s. so for me this is a near and dear subject and i’ve read all the literatureon it to make sure that my being replaced was proper and being replaced does solve allmy problems, all the symptoms of hypothyroidism. i can always tell if i didn’t take my thyroidbecause in a day i’ll know if i have those symptoms. so this is a big topic. and it’snot just big for people trying to have babies. it’s big for all of us. and it’s a hugeimpact on how we live daily and how we’re going to live when we’re older so for melooking back at 2006 when obgyn looked at this, they have all the information. but theydon’t have the information that’s centered on women who are post-menopausal thyroid replacement.it’s more about women who are cycling. because


you can stop cycling altogether if you don’thave thyroid. i mean women stop having periods. that’s one of the signs in young women.brett: yea. they stop or they have breaks or they have a period for three months andthen you don’t have one and then you have another one or it stops or what?kathy: it effects ovulation. so in general ovulation is what stimulates a menstrual cycle.so without thyroid they tend to not ovulate therefore not have a period for months ata time and then bleed heavily. or they have irregular bleeding all the time. because there’sno ovulation there’s just estrogen production, there’s no progesterone and so they’rejust bleeding all the time so it’s an irregular cycle and that makes it very hard to get pregnantif you’re not making an egg every month.


but the signs are very upsetting to patientsbecause see this and they’re put on the pill just to give them a period, just to managethat. but they’re managing once again, the symptom not the cause. and it can be justwithout hypothyroidism you can have irregular cycles but at least it should be evaluatedand that was one of the things they were looking at, should we look at this and of course theycame up with the conclusion that they should. brett: well as long as they’re looking atfertility, in women who want to be or are expected to be capable of getting pregnant.kathy: that’s primarily the interest. brett: and now we have an interest for peoplewho are getting older who aren’t looking at getting pregnant but are looking at avoidingheart issues general debilitation general


decline that whole cascade of aging deficitsthat lessen quality of life and survivability. kathy: that’s what we’re here for. that’swhat we’re here to open the door to all of this research that is out there but noone’s really talking about. brett: so if you are interested in learningmore about this, if you have questions and want to contact us generally, you can certainlydo that. kathy: you can go online to podcast@biobalancehealth.comor you can go to my website at biobalancehealth.com or you can call my office at 314-993-0963.brett: and you can always reach me at brettnewcomb.com. copyright ⩠2011 biobalance health | st.louis, mo 63141 • 314.993.0963 produced by davis interactive�





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